Disable Autorun via Group Policy

In order to disable autorun features of all drives in domain computers follow these steps below.

Open Group Policy Object Editor , and edit releated Domain Policy.

Locate Computer Policy\Computer Configuration\Administrative Templates\System in the left pane then find "Turn Off Autoplay" in the right pane.

Double click and set feature to enable set Turn of Autoplay to : All Drives

Disable Autorun in Vista;

Open : Gpedit.msc

Locate the following policy;

Local Computer Policy\Computer Configuration\Administrative Templates\Windows Components\AutoPlay Policies